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Updated: Feb 28, 2026

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Cyclodextrin Polymer Complexation Improves the Tolerability of Parenteral Oestradiol

Réka Révész1,2, Akay Dogan Mengenli1,2, Eleftheria Dossi3

  • 1Doctoral School of Pharmaceutical Sciences, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary.

Pharmaceutics
|February 27, 2026
PubMed
Summary

A novel polyethylene glycol cross-linked β-cyclodextrin (PEG-β-CD) polymer system offers a safe, water-based alternative for oestradiol delivery, potentially reducing side effects associated with oil-based menopausal hormone therapy.

Keywords:
cyclodextrin polymermenopauseoestradioloestradiol formulation

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