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Updated: Feb 28, 2026

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
Efficient synthesis of cyclic carbonates and oxazolidinones by simple zinc guanidinato complexes
Carlos Ginés1, Blanca Parra-Cadenas1, David Elorriaga2
1Departamento de Química Inorgánica, Orgánica y Bioquímica-Centro de Innovación en Química Avanzada (ORFEO-CINQA), Facultad de Ciencias y Tecnologías Químicas, Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain. Fernando.Carrillo@uclm.es.
Abstract:
Guanidinato-stabilized zinc complexes, featuring or lacking additional functionalities, were synthesized through the reaction between guanidine derivatives, specifically (iPrHN)2CNR (R = Ph, 2-FC6H4, 2-Ph2PC6H4, 2-PhSC6H4), and ZnMe2. The simple complex [ZnMe{(iPrN)(iPrNH)CNPh}] has been demonstrated to be a highly efficient catalyst for the synthesis of cyclic carbonates via the coupling of epoxides and CO2 at atmospheric pressure in neat conditions, as well as the production of oxazolidinones through the coupling of epoxides and isocyanates, in 2-MeTHF as a sustainable solvent.
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