Related Experiment Video
Updated: May 12, 2026

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
Published on: May 16, 2021
Two cases of possible transmitted HIV drug resistance to all currently available integrase inhibitors, the
Jeroen van Kampen1, Jolanda Voermans1, Widia Soochit2,1
1Department of Viroscience, Erasmus University Medical Center, Rotterdam, the Netherlands.
Abstract:
Transmitted integrase inhibitor resistance in newly diagnosed HIV remains rare. We report two cases with baseline resistance to all currently available integrase inhibitors in the Netherlands in 2025. Clinical history and laboratory findings indicate possible transmitted resistance. The cases are not phylogenetically linked, representing two independent introductions of integrase inhibitor resistant HIV into the Dutch population. These observations highlight the need for strengthened surveillance and prevention efforts in Europe and globally.
Related Concept Videos
Retrovirus Life Cycles
Sexually Transmitted Infections

