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Updated: Feb 28, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Dynamic Covalent Platform for Chiroptically Tunable Figure-Eight Macrocycles from Preorganized Alkaloidal Scaffolds

Shunsuke Murakami1, Tasuku Honda1, Takashi Fushiki1

  • 1Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku 113-0033, Tokyo, Japan.

JACS Au
|February 27, 2026
PubMed

Keywords:
chiroptically tunable emitterscircular polarized luminescencedynamic covalent chemistryfigure-eight topologymodular macrocycle synthesispreorganized alkaloidal scaffolds

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