Related Experiment Video
Updated: May 2, 2026

10:09
Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration
Published on: February 28, 2013
14.2K
Direct No-Shave Follicular Unit Excision (DNS FUE): A Modified Technique and Case Series.
1Department of Surgery, Grajau General Hospital, São Paulo, BRA.
Cureus
|February 27, 2026
Summary
A refined direct no-shave follicular unit excision (DNS FUE) technique eliminates donor-area shaving in hair transplantation. This method, using a specialized punch, achieved low graft transection rates and high patient satisfaction, offering a discreet option for hair restoration.
Area of Science:
- Surgical Dermatology
- Hair Restoration Surgery
- Androgenetic Alopecia Treatment
Background:
- Follicular Unit Excision (FUE) is a minimally invasive hair transplant method.
- The requirement to shave the donor area is a significant barrier for patients seeking discretion.
- Existing FUE techniques necessitate donor-area shaving, impacting patient aesthetics and psychosocial well-being.
Purpose of the Study:
- To describe a refined direct no-shave follicular unit excision (DNS FUE) technique.
- To evaluate the efficacy and safety of DNS FUE in reducing donor-area shaving requirements.
- To assess graft integrity and donor-site density preservation with the modified technique.
Main Methods:
- A refined direct no-shave follicular unit excision (DNS FUE) method was applied to 10 patients.
- The technique utilized the Trivellini Flared Ring punch under intravenous sedation.
- The study focused on patients with Norwood Class IV and Ludwig Class 2 androgenetic alopecia.
Main Results:
- An average of 4,600 follicular units were extracted per procedure.
- The modified technique resulted in a mean graft transection rate of 3%.
- High patient-reported satisfaction was observed, indicating aesthetic favorability.
Conclusions:
- The refined DNS FUE technique effectively eliminates the need for donor-area shaving.
- The use of the flared ring punch contributes to reduced follicular trauma and low transection rates.
- This modified DNS FUE approach presents a discreet and aesthetically favorable option for selected hair restoration candidates.
Keywords:
direct no-shave follicular unit extractiondns fue hair transplantfollicular unit excisionfollicular unit extractionfue hair transplanthair transplantlong hair transplantMore Related Videos
Related Concept Videos
Long-patch Base Excision Repair
6.3K
Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
6.3K
Multipotency and Niche of Bulge Stem Cell
2.9K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
2.9K

