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Related Concept Videos

Criteria for Causality: Bradford Hill Criteria - II01:28

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The Bradford Hill criteria serve as guidelines for establishing causative links in epidemiological research. Beyond Strength, Consistency, Specificity, and Temporality, key criteria also include Biological Gradient, Plausibility, Coherence, Experiment, and Analogy. These principles assist scientists in assessing the likelihood of causation in complex biological contexts. Below is a summary of these concepts:
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Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
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The Bradford Hill criteria are a group of principles that provide a framework to determine a causal relationship between a specific factor and a disease. There are nine criteria that are pivotal in assessing causality in epidemiological studies. Here's a closer look at Strength, Consistency, Specificity, and Temporality criteria with definitions and examples:
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Scientists frequently use models to help them comprehend a specific collection of phenomena. In physics, a model is a condensed version of a physical system that is too complex to study thoroughly. One such example is the light wave model; unlike water waves, light waves are typically invisible to us. Nonetheless, it is helpful to think of light as being composed of waves, since investigations show that light behaves like water waves. Since it is impossible to visually see what is genuinely...
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Concepts and Prototypes01:24

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According to some social psychologists, people tend to overemphasize internal factors as explanations—or attributions—for the behavior of other people. They tend to assume that the behavior of another person is a trait of that person, and to underestimate the power of the situation on the behavior of others. They tend to fail to recognize when the behavior of another is due to situational variables, and thus to the person’s state. This erroneous assumption is...
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Updated: Feb 28, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
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A framework for causal concept-based model explanations.

Anna Rodum Bjøru1, Jacob Lysnæs-Larsen1, Oskar Jørgensen1

  • 1Department of Computer Science, Norwegian University of Science and Technology, Trondheim, Norway.

Frontiers in Artificial Intelligence
|February 27, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a causal framework for explainable AI (XAI) to create understandable and faithful explanations for complex models. It uses concept interventions to generate local and global insights, ensuring clarity and accuracy.

Keywords:
causal explanationconcept attributioncounterfactual explanationpost-hoc XAIprobability of sufficiency

Related Experiment Videos

Last Updated: Feb 28, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

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Area of Science:

  • Artificial Intelligence
  • Machine Learning
  • Causal Inference

Background:

  • Non-interpretable AI models pose challenges for understanding their decision-making processes.
  • Post-hoc explainable AI (XAI) methods aim to provide insights into black-box models.
  • Existing XAI approaches may lack sufficient fidelity or understandability.

Purpose of the Study:

  • To propose a conceptual framework for causal concept-based post-hoc XAI.
  • To ensure explanations are both understandable and faithful to the underlying AI model.
  • To generate local and global explanations using concept interventions.

Main Methods:

  • Developed a conceptual framework for causal concept-based XAI.
  • Calculated the probability of sufficiency for concept interventions to generate explanations.
  • Utilized a proof-of-concept model trained on the CelebA dataset for demonstration.

Main Results:

  • Generated example local and global explanations based on concept interventions.
  • Demonstrated understandability through a clear, causally interpretable concept vocabulary.
  • Addressed fidelity by outlining framework assumptions and the importance of contextual alignment.

Conclusions:

  • The proposed framework offers a method for creating understandable and faithful explanations in XAI.
  • Causal concept interventions provide a robust mechanism for generating local and global insights.
  • Aligning explanation context with generation context is crucial for reliable XAI.