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Updated: Feb 28, 2026

05:28
Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
325
Safe Breast Cancer Diagnosis Resilient to Mammographic Adversarial Samples
Degan Hao1, Dooman Arefan2, Margarita L Zuley2
1Intelligent Systems Program, University of Pittsburgh, Pittsburgh, PA, USA.
Summary
This study introduces a new method for training AI models to accurately diagnose breast cancer, even when faced with malicious adversarial data designed to cause errors. The developed approach enhances AI resilience against such attacks in clinical settings.
Area of Science:
- Artificial Intelligence
- Medical Imaging
- Machine Learning
Background:
- Deep learning models are vulnerable to adversarial data, leading to potential malfunctions.
- Ensuring AI accuracy and resilience is crucial for safe clinical applications.
- Breast cancer diagnosis using mammography requires robust AI systems resistant to adversarial attacks.
Purpose of the Study:
- To develop a novel method for building safe and robust deep learning models for breast cancer diagnosis.
- To enhance the resilience of AI models against adversarial samples in mammography.
- To improve the accuracy of AI-driven breast cancer diagnosis in the presence of adversarial data.
Main Methods:
- Proposed a novel adversarially robust feature learning (ARFL) method.
- Incorporated a feature correlation measure as an objective function to encourage robust features.
- Facilitated adversarial training using both standard and adversarial mammographic data.
Main Results:
- Evaluated deep learning diagnosis models on two independent clinical datasets (9,548 mammograms).
- Demonstrated that the ARFL method outperformed several state-of-the-art adversarial training techniques.
- Showcased ARFL's efficacy in enhancing adversarial training for robust breast cancer diagnosis.
Conclusions:
- ARFL is an effective method for enhancing adversarial training in medical AI.
- The proposed method contributes to building safer breast cancer diagnosis systems against adversarial attacks.
- This research paves the way for more secure AI applications in clinical settings.

