Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

531
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
531
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

2.5K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.5K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

1.2K
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
1.2K
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

494
 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
494
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

487
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
487

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comment on Wagner et al. Beyond Glucose-Rethinking Prediabetes for Precision Prevention.

Diabetes care·2026
Same author

Peripheral Nerve Infiltration by CAR T-cells in a Case of Mononeuritis Multiplex after Ciltacabtagene Autoleucel.

Blood cell therapy·2026
Same author

Real-World Effectiveness and 12-Month Persistence of a Semaglutide-Supported Digital Weight-Loss Service: A Retrospective Cohort Study in Germany.

Diabetes, obesity & metabolism·2026
Same author

Burden of Disease in Myasthenia Gravis: A Targeted Literature Review.

Journal of neurology·2026
Same author

Smartphone-based App to Assess Diabetic Peripheral Neuropathy.

Journal of diabetes science and technology·2026
Same author

Integrating the Glycemia Risk Index Into Clinical Practice and Research: A Consensus Report.

Journal of diabetes science and technology·2026
Same journal

Surviving Severe Acute Brain injury: Care trajectories and missed opportunities.

medRxiv : the preprint server for health sciences·2026
Same journal

TACR3 variant confers resilience to aging and Alzheimer's disease.

medRxiv : the preprint server for health sciences·2026
Same journal

Sensorimotor recovery and neuropathic pain reduction after remotely delivered cognitive multisensory rehabilitation or remotely delivered exercise in adults with spinal cord injury: a pilot clinical trial.

medRxiv : the preprint server for health sciences·2026
Same journal

No cognitive or psychological impact from returning research Alzheimer disease biomarkers: A delayed-start, noninferiority, randomized clinical trial.

medRxiv : the preprint server for health sciences·2026
Same journal

Host Genetic Regulation of NLRP3 Inflammasome Cytokines Reveals Immune and Vascular Pathways in HIV.

medRxiv : the preprint server for health sciences·2026
Same journal

Malaria Risk among Internally Mobile Individuals and Heterogeneous Mobility Patterns in Two Hypoendemic Communities: Implications for Malaria Elimination in the Peruvian Amazon.

medRxiv : the preprint server for health sciences·2026
See all related articles
  1. Home
  3. Smartphone-based App To Assess Diabetic Peripheral Neuropathy.
  1. Home
  3. Smartphone-based App To Assess Diabetic Peripheral Neuropathy.

Related Experiment Video

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
06:00

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection

Published on: January 26, 2024

2.1K

Smartphone-based App to Assess Diabetic Peripheral Neuropathy.

Rachel A G Adenekan1, Adeyinka E Adenekan2, Kenneth K Leung3

  • 1Department of Mechanical Engineering, Stanford University, Stanford, California, USA.

Medrxiv : the Preprint Server for Health Sciences
|February 27, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

A smartphone app accurately measures vibration perception thresholds (SVPTs) for early diabetic peripheral neuropathy (DPN) detection. This accessible tool aids in monitoring nerve damage and preventing amputations in diabetes patients.

Keywords:
diabetes foot examdiabetic peripheral neuropathydigital healthearly detectionremote patient monitoringself-monitoring

More Related Videos

Smartphone Fundus Photography
05:51

Smartphone Fundus Photography

Published on: July 6, 2017

40.3K
Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
11:29

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Published on: January 3, 2011

27.4K

Related Experiment Videos

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection
06:00

Author Spotlight: Development of a Smartphone-Enhanced Paper-Based Device for Rapid Dengue NS1 Detection

Published on: January 26, 2024

2.1K
Smartphone Fundus Photography
05:51

Smartphone Fundus Photography

Published on: July 6, 2017

40.3K
Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
11:29

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies

Published on: January 3, 2011

27.4K

Area of Science:

  • Neurology
  • Biomedical Engineering
  • Diabetes Research

Background:

  • Diabetic peripheral neuropathy (DPN) affects 50% of diabetes patients, increasing amputation risk.
  • Current screening methods are inconsistent and often miss early nerve damage.
  • A smartphone application for measuring vibration perception thresholds (SVPTs) offers a precise and accessible monitoring solution.

Purpose of the Study:

  • To assess the clinical relevance and precision of smartphone-based SVPTs for detecting large-fiber sensory deficits in diabetic patients.
  • To compare the efficacy of SVPT measurements with traditional tuning fork exams.

Main Methods:

  • Seventy-one patients with pre-diabetes or diabetes had their SVPTs measured using a smartphone app.
  • SVPT measurements were compared with Rydel-Seiffer tuning fork (RSTF) scores.
  • Multivariable linear regression analyzed correlations between SVPTs, RSTF scores, and clinical markers like HbA1c, age, and diabetes duration.

    • Main Results:

    • SVPTs showed a moderate correlation with RSTF scores (Rs = -0.43, p = 0.0019).
    • In adults aged 50-69, SVPTs significantly correlated with clinical markers (F(4, 29) = 4.76, p = 0.00447).
    • Age and HbA1c interaction positively associated with SVPTs (β = 0.118, p = 0.001), while diabetes duration negatively associated (β = -0.098, p = 0.003).

    Conclusions:

    • A novel, patient-operated smartphone application provides clinically relevant monitoring for large-fiber sensory deficits.
    • This platform offers a precise, reliable, and accessible method for identifying individuals at risk of DPN complications.
    • Early detection via SVPTs can help prevent severe DPN-related outcomes, such as amputations.