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Updated: Feb 28, 2026

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CT-guided Preoperative Localization of Pulmonary Nodules Using a Glucose Test and Tissue Adhesive
Published on: January 30, 2026
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Computed tomography-guided suture anchor localizer placement for multiple pulmonary nodule localization
Zheng Gong1, Tong Zhou2, Yong-Guang Gao3
1Department of Cardiothoracic Surgery Xuzhou Cancer Hospital China.
Summary
Computed tomography (CT)-guided suture anchor localizer (SAL) placement is safe and effective for locating multiple pulmonary nodules (PNs) before surgery. This technique supports successful video-assisted thoracoscopic surgery (VATS) for patients with multiple PNs.
Area of Science:
- Thoracic Surgery
- Medical Imaging
- Interventional Radiology
Background:
- Computed tomography (CT)-guided suture anchor localizer (SAL) placement is a common method for preoperative localization of pulmonary nodules (PNs) before video-assisted thoracoscopic surgery (VATS).
- Limited evidence exists for the application of SAL placement in cases involving multiple PNs.
Purpose of the Study:
- To evaluate the safety and efficacy of CT-guided SAL placement for the simultaneous localization of multiple PNs.
- To compare outcomes between multiple PN localization and single PN localization.
Main Methods:
- A retrospective, 2-center study included patients undergoing CT-guided SAL placement for multiple PNs followed by VATS resection.
- A control group of patients with single PN localization was used for comparison.
- Clinical outcomes and procedural complications were analyzed.
Main Results:
- Technical success for SAL placement was 100% in both multiple (106 PNs in 49 patients) and single (163 PNs in 163 patients) nodule groups.
- Localization time was significantly longer for multiple PNs.
- Pneumothorax and intrapulmonary hemorrhage rates were higher in the multiple-PN group but VATS sublobar resection success remained 100% in both groups.
Conclusions:
- CT-guided SAL placement is a reliable and safe method for preoperative localization of multiple PNs.
- The findings support the clinical utility of this technique for patients undergoing VATS for multiple pulmonary nodules.

