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Related Concept Videos

Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

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Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
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Measurement of Blood Pressure01:17

Measurement of Blood Pressure

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Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
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Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response01:15

Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response

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Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
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Assessment of blood pressure in brachial artery(one-step method)01:15

Assessment of blood pressure in brachial artery(one-step method)

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This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
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Blood Pressure01:24

Blood Pressure

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The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
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Blood Pressure01:30

Blood Pressure

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Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
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Related Experiment Video

Updated: Feb 28, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

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Association Between 24-Hour Systolic Blood Pressure Time in Target Range and Mortality.

Lucas Lauder1,2, Igor Schwantke3, Alejandro de la Sierra4

  • 1Department of Cardiology, University Heart Center (L.L., F.M.), University Hospital Basel, Switzerland.

Hypertension (Dallas, Tex. : 1979)
|February 27, 2026
PubMed
Summary

Higher time in target range (TTR) for systolic blood pressure (SBP) is linked to reduced mortality. This finding highlights the importance of maintaining blood pressure within the target range for better cardiovascular health outcomes.

Keywords:
blood pressure monitoring, ambulatoryhypertension prognosisstroke

Related Experiment Videos

Last Updated: Feb 28, 2026

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

692

Area of Science:

  • Cardiology
  • Hypertension Management
  • Public Health

Background:

  • Time in Target Range (TTR) integrates blood pressure (BP) variability and control.
  • Systolic BP (SBP) TTR is a measure of BP control during ambulatory BP monitoring.
  • Understanding SBP TTR's impact on mortality is crucial for cardiovascular risk assessment.

Purpose of the Study:

  • To investigate the association between SBP TTR during ambulatory BP monitoring and cardiovascular and all-cause mortality.
  • To determine if SBP TTR is an independent predictor of mortality beyond mean BP and BP variability.

Main Methods:

  • Analysis of data from the Spanish Ambulatory BP Monitoring Registry, including 48,687 patients.
  • Estimation of 24-hour SBP TTR using linear interpolation between consecutive SBP recordings.
  • Cox regression analysis adjusted for demographic and clinical variables to assess mortality associations.

Main Results:

  • Higher 24-hour SBP TTR was significantly associated with lower all-cause mortality (HR, 0.83 per 1-SD increment).
  • Higher 24-hour SBP TTR was also associated with lower cardiovascular mortality (HR, 0.80 per 1-SD increment).
  • These associations remained significant after adjustment for mean 24-hour SBP and SBP variability.

Conclusions:

  • Increased 24-hour SBP TTR, as measured by ambulatory BP monitoring, is independently linked to reduced all-cause and cardiovascular mortality.
  • Ambulatory BP monitoring and TTR assessment can provide valuable prognostic information in hypertensive patients.
  • Optimizing SBP TTR may be a therapeutic target for improving long-term outcomes in patients with hypertension.