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Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury
Published on: November 9, 2018
[Suspected phenibut poisoning with brainstem involvement]
Jimmi Malmberg Scheel Jensen1, Mette Lolk1, Dorte Fris Palmqvist2
1Afdeling for Bedøvelse, Operation og Intensiv Behandling, Københavns Universitetshospital - Herlev og Gentofte Hospital.
None:
Phenibut (β-phenyl-γ-aminobutyric acid) is a GABA-B agonist associated with sedation, dependency, and withdrawal. In this case report, a young man was admitted unconscious with partial brainstem areflexia. Based on clinical findings, a container of phenibut found on him, and his later statement of ingestion, phenibut intoxication was suspected, and he was admitted to the ICU. He later developed withdrawal symptoms, treated effectively with baclofen. This highlights phenibut as a potential cause of coma and the role of baclofen in withdrawal treatment.
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