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Dual-pathway sensing in Ti-MOFs for selective VOC discrimination by SERS
Zijing Guo1, Xiaobing Ren2, Jiale Hu1
1Nanjing Tech University, School of Chemistry and Molecular Engineering, Nanjing, 211816, P. R. China. yihuidong0901@njtech.edu.cn.
Chemical Communications (Cambridge, England)
|February 27, 2026
Summary
We developed a titanium metal-organic framework (Ti-MOF) sensor for detecting volatile organic compounds (VOCs). This platform utilizes confinement effects and π-interactions for highly sensitive and selective VOC analysis.
Area of Science:
- Materials Science
- Analytical Chemistry
- Nanotechnology
Background:
- Volatile organic compounds (VOCs) pose environmental and health risks.
- Sensitive and selective detection methods for VOCs are crucial.
- Metal-organic frameworks (MOFs) offer tunable properties for sensing applications.
Purpose of the Study:
- To develop a novel Ti-MOF-based Surface-Enhanced Raman Spectroscopy (SERS) platform.
- To achieve highly sensitive and selective detection of VOCs.
- To investigate distinct analyte-specific detection mechanisms.
Main Methods:
- Fabrication of a Ti-MOF material.
- Integration of Ti-MOF with SERS technology.
- Analysis of VOC detection using confinement effects.
- Analysis of VOC detection using π-interactions.
Main Results:
- The Ti-MOF platform demonstrated high sensitivity and selectivity for VOC detection.
- Two distinct mechanisms, confinement effects and π-interactions, were identified for analyte-specific detection.
- The platform showed promise for real-world VOC monitoring.
Conclusions:
- Ti-MOF-based SERS is a viable platform for sensitive and selective VOC detection.
- Understanding the interplay between confinement effects and π-interactions enhances sensor design.
- This work paves the way for advanced environmental monitoring solutions.
