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Updated: Feb 28, 2026

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Automated Chest X-ray Report Generation Remains Unsolved.

Xiaoman Zhang1, Julian Nicolas Acosta1, Xiaoli Yang1

  • 1Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

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Summary
This summary is machine-generated.

Automated chest X-ray report generation shows promise but faces significant challenges. Current AI models struggle with accuracy, especially for abnormal cases and across different healthcare sites, indicating further development is needed for clinical readiness.

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Area of Science:

  • Medical Imaging Analysis
  • Artificial Intelligence in Healthcare
  • Radiology Reporting

Background:

  • Accurate chest radiograph interpretation is crucial for patient care but burdensome for radiologists.
  • Existing AI models for automated report generation lack standardized evaluation frameworks.
  • Limited benchmarks hinder the assessment of AI performance in clinical settings.

Purpose of the Study:

  • To introduce the ReXrank Challenge V1.0 for evaluating AI models in chest radiograph report generation.
  • To utilize ReXGradient, the largest test dataset (10,000 studies, 67 sites), for comprehensive benchmarking.
  • To analyze model performance across normal/abnormal studies, generalization, and clinical finding identification.

Main Methods:

  • Organized a competition (ReXrank Challenge V1.0) involving diverse participants and state-of-the-art AI models.
  • Employed a large-scale dataset (ReXGradient) for training and testing.
  • Utilized multiple metrics for comprehensive performance evaluation across various dimensions.

Main Results:

  • Automated chest X-ray report generation is not yet a solved problem.
  • Significant performance disparities exist between normal and abnormal study interpretations.
  • Top models achieve less than 45% error-free reporting on abnormal cases, with notable variability across healthcare institutions.

Conclusions:

  • Current AI systems for chest X-ray report generation require substantial improvement before clinical deployment.
  • Addressing performance gaps in abnormal cases and ensuring cross-institutional generalization are critical research areas.
  • Continued development is necessary to create robust and clinically reliable automated reporting systems.