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Session Introduction: Biological molecular function: methods and benchmarks for finding function in biological dark

Jason E McDermott1, Yana Bromberg2, Hannah Carter3

  • 1Computational Biology Group, Pacific Northwest National Laboratory Richland, Washington 99352, USA2Department of Molecular Microbiology and Immunology, Oregon Health & Science University Portland, Oregon 97239, USA, Jason.McDemott@pnnl.gov.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
|February 27, 2026
PubMed
Summary

Computational biology faces challenges in determining molecular function. New AI/ML methods, including geometric protein modeling and reinforcement learning for sequence design, offer innovative solutions for biological "dark matter".

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