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Monkeypox Infection in Kidney Transplant Recipients
Ai-Qin Sheng1, Zhi-Qiang Zhao2, Fei Liu1
1Department of Nephrology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Kidney & Blood Pressure Research
|February 27, 2026
Summary
Kidney transplant recipients are at high risk for monkeypox complications. This study of 11 patients found most had good outcomes with antiviral treatment, highlighting the need for better prevention and management strategies.
Area of Science:
- Infectious Diseases
- Nephrology
- Transplantation
Background:
- Monkeypox virus poses a global health emergency.
- Kidney transplant recipients are vulnerable due to immunosuppression.
- High risk for severe monkeypox complications in this population.
Purpose of the Study:
- To summarize clinical data of monkeypox patients.
- To analyze outcomes in kidney transplant recipients.
- To inform prevention and treatment strategies.
Main Methods:
- Retrospective review of 11 patient cases.
- Analysis of clinical features and treatment outcomes.
- Evaluation of immunosuppressive agent adjustment and antiviral use.
Main Results:
- 10 of 11 cases were male, aged 25-62.
- Common symptoms included rashes, anorectal pain, fever, and respiratory issues.
- Most patients (10/11) had good prognosis with antiviral therapy (tecovirimat, cidofovir, brincidofovir).
Conclusions:
- Monkeypox is a significant threat to kidney transplant recipients.
- Prompt diagnosis and management are crucial.
- Further research is needed to standardize treatment protocols.
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