EVALUATION OF THE INSECT GROWTH REGULATOR SUMILARV 0.5G AGAINST ANOPHELES COLUZZII AND AN. ARABIENSIS LARVAE UNDER...

Recent research has demonstrated that larvicides can be an effective tool in integrated malaria vector control. However, the widespread adoption of this intervention has been limited by the need for frequent reapplication. To reduce operational efforts and costs, there is a growing need to explore long-lasting and environmentally friendly larvicides. In this study, an insect growth regulator, 0.5% pyriproxyfen (Surmilarv 0.5G), was evaluated both under laboratory conditions and at an experimental station for its efficacy against Anopheles coluzzii and An. arabiensis larvae, 2 major malaria vectors. In the laboratory, complete mortality was achieved at concentrations between 5 and 10 µg/liter for both species. In field trials with An. coluzzii, a concentration of 10 µg/liter resulted in almost complete inhibition of adult emergence during the monitoring period. The emergence inhibition rate (EIR) of 100% was achieved within 17 days, with pupal mortality exceeding 95%. Peak adult mortality was recorded on day 35 (32%), with 46% adult emergence still observed by day 81. At 0.1 µg/liter, 100% of EIR was achieved on day 8, with 48% adult emergence by day 81. For An. arabiensis, the 10 µg/liter concentration also resulted in full inhibition of adult emergence throughout the 35-day follow-up period. At 1 µg/liter, 100% of EIR was observed by day 9. Anopheles coluzzii and An. arabiensis are highly sensitive to Sumilarv 0.5G at low concentrations. The persistence of this granular formulation in treated habitats under standard field conditions highlights its potential as a valuable tool in malaria vector control.