Synthesis and Biomedical Potential of TiCO₃ Nanoparticles in Diabetes and Infection

Titanium carbonate nanoparticles (TiCO₃ NPs) were synthesized and extensively characterized using advanced spectroscopic and microscopic techniques to confirm their crystalline structure, morphology, and stability. Biocompatibility assessments revealed minimal cytotoxicity, supporting their potential for biomedical applications. The therapeutic efficacy of TiCO₃ NPs was investigated in a diabetic mouse model, where oral administration significantly improved glycemic control, reduced fasting blood glucose levels, and enhanced insulin sensitivity compared to untreated controls. In parallel, the antibacterial potential of TiCO₃ NPs was evaluated against clinically relevant pathogens, including Enterobacter sp., and Staphylococcus aureus. These results confirm the broad-spectrum antibacterial potential of TiCO₃, highlighting their capacity to disrupt both Gram-positive and Gram-negative bacteria. Collectively, these findings establish TiCO₃ NPs as a multifunctional nanomaterial with excellent biocompatibility, effective glycemic regulation in diabetic models, and broad-spectrum antibacterial activity, positioning them as promising candidates for therapeutic and biomedical applications.