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Related Concept Videos

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Refractive Changes Associated With Pediatric Kidney Transplantation.

Olgar Öcal1, Aslı Çetinkaya Yaprak1, Rabia Büşra Yavuz1

  • 1Department of Ophthalmology, Akdeniz University Hospital, Antalya, Turkey.

Pediatric Transplantation
|February 28, 2026
PubMed
Summary

Pediatric kidney transplant recipients showed acceptable rates of cataract development and refractive changes, even with long-term immunosuppression. Regular monitoring of vision is crucial for early detection and prevention of amblyopia in these young patients.

Keywords:
cataractimmunosuppressive treatmentpediatric kidney transplantationrefractive changesspherical equivalent

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Area of Science:

  • Ophthalmology
  • Pediatric Nephrology
  • Transplant Surgery

Background:

  • Kidney transplantation is the primary treatment for pediatric end-stage renal disease (ESRD).
  • Congenital malformations and genetic syndromes account for 25%-40% of pediatric ESRD cases.
  • Ocular complications can arise post-kidney transplantation due to surgery or medical treatments.

Purpose of the Study:

  • To evaluate postoperative refractive changes in pediatric kidney transplant recipients.
  • To identify refractive changes that could lead to amblyopia during follow-up.

Main Methods:

  • Retrospective review of 84 pediatric patients who underwent kidney transplantation.
  • Ophthalmologic examinations conducted at least one year post-transplantation.
  • Data collected included visual acuity, refractive error (SER), and anterior/posterior segment examinations.

Main Results:

  • Cataracts developed in 10.7% of patients, with posterior subcapsular cataracts being most common.
  • A statistically significant decrease in visual acuity was observed in patients who developed cataracts post-transplantation (p=0.027).
  • No significant changes in spherical equivalent refraction (SER) were noted overall post-transplantation.

Conclusions:

  • Pediatric kidney transplant recipients exhibit lower cataract development rates compared to adults, despite prolonged immunosuppression.
  • Cataract development and refractive changes in pediatric transplant patients are within acceptable limits.
  • Close monitoring of refractive changes is essential in young pediatric patients to prevent irreversible vision loss.