Crizotinib-associated nodular scleritis in an adolescent.

Mennatullah Elfwwal1, Douglas S Hawkins2, Laura C Huang1

  • 1Department of Ophthalmology, University of Washington, Seattle, Washington; Division of Ophthalmology, Seattle Children's Hospital, Seattle, Washington.

Summary

Crizotinib therapy for anaplastic large-cell lymphoma may cause scleritis, an eye inflammation. Discontinuing the drug resolved the condition, suggesting a link between crizotinib and this ocular side effect.