Related Experiment Video
Updated: Jun 3, 2026

Using Robotic Systems to Process and Embed Colonic Murine Samples for Histological Analyses
Published on: January 7, 2019
The Path to Diagnosis: Best Practices in Gastrointestinal Histopathology Collection and Examination
1Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, TX, USA.
Abstract:
This article emphasizes the importance of strategic gastrointestinal biopsy collection, handling, and interpretation in dogs and cats. It highlights the need for high-quality, well-oriented samples, proper fixation, and detailed submission forms to ensure accurate diagnosis of inflammatory, neoplastic, and infectious diseases. The review discusses techniques for endoscopic biopsies, histopathologic evaluation, and ancillary testing, including immunohistochemistry and special stains. Proper communication among clinicians, histotechnologists, and pathologists is crucial for reliable results. Overall, optimized biopsy procedures and collaboration are essential for precise diagnosis, guiding effective treatment and improving patient outcomes in veterinary gastrointestinal medicine.
Related Concept Videos
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Serum Laboratory Studies, Stool Test, Breath Test
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

