Feasibility and Safety of CIOS Spin for One-Stop Pulmonary Nodule Localization and Resection

Area of Science:

• Thoracic Surgery
• Pulmonary Medicine
• Medical Imaging

Background:

• Ground-glass nodules (GGNs) are early indicators of lung adenocarcinoma.
• Minimally invasive diagnosis of GGNs is increasingly important due to expanded health screening.
• The mobile 3D Cios Spin system, originally for orthopedics, is evaluated for pulmonary nodule procedures.

Purpose of the Study:

• To assess the feasibility and safety of using the mobile 3D Cios Spin system for integrated pulmonary nodule localization and resection.
• To evaluate the technical success and perioperative outcomes of this novel application.

Main Methods:

• Retrospective analysis of 23 patients undergoing thoracic procedures between January and December 2023.
• Preoperative nodule identification via chest CT, with confirmation of persistence over ≥3 months.
• Intraoperative confirmation of precise localization needle placement (within ≤5 mm of nodule margin).

Main Results:

• 100% technical success rate for preoperative localization.
• One case of pneumothorax (4.3%) occurred during needle insertion.
• Mean localization and surgery durations were 35.3 ± 6.4 min and 90.8 ± 20.2 min, respectively.

Conclusions:

• The mobile 3D Cios Spin system demonstrates feasibility, safety, and clinical efficacy for combined pulmonary nodule localization and resection.
• Device and patient factors can influence localization, indicating a need for technical refinements and optimized selection criteria.
• No recurrence was observed at 6-month follow-up, though 2-year follow-up is pending.