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Super-resolution Fluorescence Microscopy

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...

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Related Experiment Video

Updated: Mar 2, 2026

Whole-cell Super-Resolution Imaging via DNA-PAINT on a Spinning Disk Confocal with Optical Photon Reassignment

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Image-based epigenetic profiling with deep learning and high-speed super-resolution microscopy

Yicheng Wang¹, Nur Syatila Ab Ghani², Munmee Dutta³

¹Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, 277-0882, Chiba, Japan.

Epigenetics & Chromatin

|March 1, 2026

Summary

No abstract available in PubMed .

Keywords:

Deep learning Histone deacetylase inhibitor Image-based epigenetic profiling Rett syndrome Super-resolution microscopy

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