Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Motor Unit Stimulation

Motor Unit Stimulation

When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cell Membrane Capacitance and Characteristic Frequency Among Youth and Adults: Reference Data From NHANES 1999-2000.

Journal of the American Nutrition Association·2026

Same author

Creatine monohydrate for lean mass, strength, and bone density in postmenopausal women: a systematic review and meta-analysis.

Journal of the International Society of Sports Nutrition·2026

Same author

Effects of acute HMB-FA supplementation on antioxidant status and muscle damage in Elite Judoka: a randomized pilot trial.

Journal of the International Society of Sports Nutrition·2026

Same author

The emerging and evolving evidence supporting creatine as an ergogenic aid: history and applications.

Journal of the International Society of Sports Nutrition·2026

Same author

Taurine Supplementation and Human Heat Tolerance: Mechanisms, Evidence, and Integration with Heat Acclimation, Cooling, and Hydration.

Nutrients·2026

Same author

International Society of Sports Nutrition position stand: effects of dietary antioxidants on exercise and sports performance.

Journal of the International Society of Sports Nutrition·2026

Search research articles

Related Experiment Video

Updated: Mar 3, 2026

Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer

Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer

Published on: February 20, 2020

Reliability and Diurnal-Fatigability Effects on Force-Time Characteristics During Maximal Voluntary Handgrip

Modesto A Lebron¹, Justine M Starling-Smith¹, Grant E Norte¹

¹School of Kinesiology and Rehabilitation Sciences, University of Central Florida, Orlando, FL. USA.

|March 1, 2026

Summary

This summary is machine-generated.

Handgrip strength tests using force-time data show good reliability. Force maintenance variables, like time to 90% peak force (TT90) and area under the curve deficit (AUC Deficit), are sensitive to fatigability and time-of-day interactions.

Keywords:

force maintenance isometric time-of-day

More Related Videos

Measurement of Spatial Stability in Precision Grip

Measurement of Spatial Stability in Precision Grip

Published on: June 4, 2020

In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig

In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig

Published on: September 3, 2021

Related Experiment Videos

Last Updated: Mar 3, 2026

Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer

Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer

Published on: February 20, 2020

Measurement of Spatial Stability in Precision Grip

Measurement of Spatial Stability in Precision Grip

Published on: June 4, 2020

In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig

In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig

Published on: September 3, 2021

Area of Science:

Biomechanics
Human Physiology
Musculoskeletal Health

Background:

Isometric handgrip strength tests are standard for assessing overall muscular strength.
Peak force (PF) is a common metric, but force-time characteristics offer deeper insights into muscle function.
Understanding reliability and influencing factors is crucial for accurate strength assessment.

Purpose of the Study:

To evaluate the test-retest reliability of various force-time characteristics during maximal voluntary handgrip contractions.
To investigate the impact of fatigability and time-of-day on these force-time characteristics.
To determine if additional force-time metrics provide more information than peak force alone.

Main Methods:

Participants performed maximal voluntary handgrip contractions (3 repetitions, 4-second duration, 1-minute rest).
Analysis 1 assessed test-retest reliability of force-time variables.
Analysis 2 examined the effects of a fatiguing intervention and time-of-day on these variables.

Main Results:

All measured force-time variables demonstrated moderate to excellent relative reliability.
Fatigability significantly affected most variables, except plateau derivative root mean square.
A significant interaction between time-of-day and fatigability was found for time to 90% peak force (TT90), area under the curve deficit (AUC Deficit), and force coefficient of variation.

Conclusions:

Force-time characteristics, particularly TT90 and force maintenance variables (AUC Deficit, force coefficient of variation), offer valuable insights beyond peak force.
These metrics are sensitive to the interplay of fatigability and time-of-day.
While time-of-day may not directly impact performance, its interaction with fatigability is significant for understanding handgrip strength dynamics.