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Updated: May 1, 2026
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Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
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Percutaneous Cryoablation of Papillary Thyroid Cancer
Saim Yılmaz1, Hatice Arıöz Habibi1, Ömür Gencel2
1Department of Radiology, Private Varisson Radiology Center, Antalya, Turkey.
Journal of Vascular and Interventional Radiology : JVIR
|March 1, 2026
Summary
Cryoablation offers a safe and effective treatment for papillary thyroid cancer (PTC). This minimally invasive procedure shows significant tumor reduction and no recurrence, making it a viable alternative to surgery.
Area of Science:
- Oncology
- Minimally Invasive Procedures
Background:
- Papillary thyroid cancer (PTC) is a common endocrine malignancy.
- Current treatment options include surgery and heat-based ablation techniques.
Purpose of the Study:
- To evaluate the safety and efficacy of cryoablation for treating papillary thyroid cancer.
- To compare outcomes with and without hydrodissection during cryoablation.
Main Methods:
- Retrospective review of 71 PTCs in 65 patients treated with cryoablation over 7 years.
- Tumor characteristics (T1, T2, T3) and hydrodissection techniques were analyzed.
- Ultrasound follow-up at 6-month intervals assessed tumor response and recurrence.
Main Results:
- Cryoablation achieved technical success in all cases with minimal adverse events (3%).
- Significant tumor volume reduction observed at 6 months (87.7% for T1, 85.4% for T1+T2).
- Medial and lateral hydrodissection reduced periprocedural hoarseness (p<0.001); no local recurrence or metastasis noted during mean follow-up of 34.8 months.
Conclusions:
- Cryoablation is a safe and effective treatment modality for papillary thyroid cancer.
- It presents a promising alternative to surgery and heat-based ablations, especially for T1b, T2, and T3 tumors.
- Medial and lateral hydrodissection are recommended to mitigate the risk of hoarseness.
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