Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

1.3K
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
1.3K
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

342
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
342
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

570
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
570
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

349
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
349
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

1.0K
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
1.0K
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

3.7K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Heart health must not be a question of socioeconomic status].

Deutsche medizinische Wochenschrift (1946)·2026
Same author

Off-label testosterone therapy is associated with higher long-term cardiovascular risk in men.

EBioMedicine·2026
Same author

Pyoderma gangrenosum is associated with excess incident major atherothrombotic events.

Atherosclerosis·2026
Same author

Impact of residential noise pollution on early-onset myocardial infarction risk results from the DECIBEL-MI (Determination of Environmental CIty-noise's Burden, Exposure, and Link to Myocardial Infarction) study.

Clinical research in cardiology : official journal of the German Cardiac Society·2026
Same author

Right atrial pressure corrected cardiac power index improves predictive power for 1-year mortality after transcatheter edge-to-edge-repair for severe tricuspid valve regurgitation.

The international journal of cardiovascular imaging·2025
Same author

Authors' reply to the comment by Zhuang and Jin on "Severe obesity in patients with ST-segment-elevation myocardial infarction (STEMI): association with age, temporal trends, and clinical outcomes."

European journal of preventive cardiology·2025

Related Experiment Video

Updated: Mar 3, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.8K

Socioeconomic Status and Long-Term Outcomes After ST-Segment Elevation Myocardial Infarction.

Hatim Kerniss1, Ulrich Hanses1, Stephan Rühle1

  • 1Bremen Institute for Heart and Circulation Research (BIHKF), Bremen, Germany.

The American Journal of Cardiology
|March 1, 2026
PubMed
Summary

Socioeconomic disadvantage is linked to poorer long-term outcomes in ST-segment elevation myocardial infarction (STEMI) patients, despite similar acute care. Targeted post-discharge prevention is crucial for these individuals.

Keywords:
MACCESTEMISocioeconomic statuscardiovascular riskprognosis

More Related Videos

Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.7K
Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.6K

Related Experiment Videos

Last Updated: Mar 3, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.8K
Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.7K
Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

4.6K

Area of Science:

  • Cardiology
  • Public Health
  • Health Disparities

Background:

  • Socioeconomic status (SES) impacts cardiovascular risk, but its role in ST-segment elevation myocardial infarction (STEMI) care needs further investigation.
  • Understanding SES-related disparities in STEMI management is vital for equitable healthcare.
  • Contemporary data on SES and STEMI outcomes are limited.

Purpose of the Study:

  • To examine socioeconomic status (SES)-related differences in risk profile, acute care, and 5-year outcomes among STEMI patients.
  • To identify disparities in STEMI care and long-term prognosis based on SES.
  • To inform targeted interventions for high-risk socioeconomic groups.

Main Methods:

  • Retrospective analysis of 2,807 consecutive STEMI patients treated at a regional heart center (2015-2022).
  • SES categorized using the neighborhood-level Social Deprivation Index (high, intermediate, low, very low).
  • Multivariable models adjusted for demographics, risk factors, and interventional success to analyze 5-year major adverse cardiac and cerebrovascular events (MACCE).

Main Results:

  • Patients with very low SES were younger and had higher rates of diabetes and smoking compared to high SES.
  • Acute presentation, infarct characteristics, and in-hospital outcomes were similar across SES strata.
  • Very low SES was independently associated with a significantly higher risk of 5-year MACCE (HR 2.45) compared to high SES.

Conclusions:

  • Socioeconomic disadvantage is associated with earlier STEMI presentation and worse long-term outcomes.
  • Despite comparable acute care, individuals with lower SES face greater long-term cardiovascular event risk.
  • Targeted post-discharge secondary prevention strategies are essential for patients with socioeconomic disadvantage.