Related Experiment Video
Updated: Mar 3, 2026

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
Published on: September 16, 2022
Biofilm and Dermatophytoma
Tomotaka Sato1, Norihito Fukada1, Hisashi Kobayashi2
1Department of Dermatology, Teikyo University Chiba Medical Center.
Abstract:
Dermatophytoma is a type of onychomycosis with distinctive clinical features. Clinically, it typically appears as a linear spike, triangular, or round white- or yellow-colored mass on the nail plate. Dermatophytes are thought to adhere to the nail surface and secrete extracellular polysaccharides (EPS), proteins, DNA, and other components, forming a biofilm matrix. EPS typically encases this microbial aggregation and is synthesized by the microbial constituents of the biofilm. Herein, we review dermatophytoma and the relationship between nail infection and biofilm. We also discuss green nails with dermatophytoma and infection models of biofilm formation.
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