Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Noncovalent Attractions in Biomolecules02:35

Noncovalent Attractions in Biomolecules

65.7K
Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
65.7K
Protein Folding01:22

Protein Folding

129.0K
Overview
129.0K
Hydrogen Bonds00:26

Hydrogen Bonds

135.7K
Hydrogen bonds are weak attractions between atoms that have formed other chemical bonds. One of these atoms is electronegative, like oxygen, and has a partial negative charge. The other is a hydrogen atom that has bonded with another electronegative atom and has a partial positive charge.
Hydrogen Bonds Control the World!
Because hydrogen has very weak electronegativity when it binds with a strongly electronegative atom, such as oxygen or nitrogen, electrons in the bond are unequally shared....
135.7K
Hydrogen Bonds01:04

Hydrogen Bonds

15.5K
A hydrogen bond is formed when a weakly positive hydrogen atom already bonded to one electronegative atom (for example, the oxygen in the water molecule) is attracted to another electronegative atom from another polar molecule, such as water (H2O), hydrogen fluoride (HF), or ammonia (NH3). The huge electronegativity difference between the H atom (2.1) and the atom to which it is bonded (4.0 for an F atom, 3.5 for an O atom, or 3.0 for an N atom), combined with the very small size of an H atom...
15.5K
Protein Organization01:24

Protein Organization

9.8K
Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence....
9.8K
Polymer Classification: Architecture01:14

Polymer Classification: Architecture

4.0K
Polymers are classified as linear or branched on the basis of their chain architecture. The polymer chains in linear polymers have a long chain-like structure with minimal to no branching at all. Even if a polymer features large substituent groups on the monomer, which appear as branches to the skeleton, it is not considered a branched polymer. A branched polymer contains secondary polymer chains that arise from the main polymer chain. The branching occurs when the polymer growth shifts from...
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heteronuclear MOF Heterostructures Based on Identical Auxiliary-Ligand Bridging for Multi-Function-Integrated Photonic Devices.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Cascade Oxidation of Ethylene and Propylene over a Redox Heterometallic Cluster.

Journal of the American Chemical Society·2026
Same author

Novel Carborane Based Metal Organic Framework for Record Electronic Specialty Gas C<sub>2</sub>F<sub>6</sub> Purification via Molecular Sieving.

Angewandte Chemie (International ed. in English)·2026
Same author

Engineering CO<sub>2</sub> Pre-Activation in In-MOF for Enhancing its Electroreduction Activity.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Symmetry Engineering of Metal-Organic Frameworks via Ligand Desymmetrization Design for Acetylene Purification.

Inorganic chemistry·2026
Same author

Synergistic High-Connectivity and Nonplanar Conformation Generates a Stable Hydrogen-Bonded Organic Framework for Benchmark Methanol-to-Olefin Product Separation.

Angewandte Chemie (International ed. in English)·2026

Related Experiment Video

Updated: Mar 3, 2026

Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

49.3K

Reticular Design of Hydrogen-Bonded Organic Frameworks (HOFs): From Structure Tuning to Function Customization.

Dongmei Wang1, Jiantang Li1, Banglin Chen1,2

  • 1Zhejiang Key Laboratory of Advanced Catalysis and Adsorption Materials, Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, College of Chemistry and Materials Science, Zhejiang Normal University, Jinhua, P.R. China.

Angewandte Chemie (International Ed. in English)
|March 2, 2026
PubMed
Summary
This summary is machine-generated.

Hydrogen-bonded organic frameworks (HOFs) are now designed using reticular chemistry. This approach enables predictable synthesis of stable, multifunctional porous materials by controlling weak interactions.

Keywords:
HOFH‐bonding pairporous materialreticular chemistrytopology

More Related Videos

Author Spotlight: Accelerating Discovery in Microporous Material Chemistry
07:20

Author Spotlight: Accelerating Discovery in Microporous Material Chemistry

Published on: October 6, 2023

4.5K
Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
10:58

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

17.7K

Related Experiment Videos

Last Updated: Mar 3, 2026

Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

49.3K
Author Spotlight: Accelerating Discovery in Microporous Material Chemistry
07:20

Author Spotlight: Accelerating Discovery in Microporous Material Chemistry

Published on: October 6, 2023

4.5K
Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
10:58

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

17.7K

Area of Science:

  • Materials Science
  • Supramolecular Chemistry
  • Crystallography

Background:

  • Hydrogen-bonded organic frameworks (HOFs) are porous crystalline materials assembled via reversible hydrogen bonds.
  • HOFs offer advantages like mild synthesis and recyclability but face challenges in targeted design.
  • Reticular chemistry principles are increasingly applied to HOFs, moving beyond empirical assembly.

Purpose of the Study:

  • To review the evolution of HOF design from molecular connectivity to topological principles.
  • To highlight advances in reticular strategies for HOF synthesis and functionality.
  • To discuss the role of rational control over weak interactions in developing programmable HOFs.

Main Methods:

  • Review of literature on reticular chemistry applied to HOFs.
  • Analysis of how directional H-bonds and tecton geometry influence framework construction.
  • Summary of recent strategies for enhancing HOF stability, pore properties, and flexibility.

Main Results:

  • Directional H-bonds and defined tecton geometry enable predictable and stable HOF construction.
  • Reticular design strategies have advanced HOF stability, pore tuning, and functionality.
  • Framework flexibility can be introduced through rational reticular design.

Conclusions:

  • Reticular chemistry transforms HOFs into rationally designed, predictable materials.
  • Control over weak interactions is key to developing multifunctional and programmable HOFs.
  • HOF chemistry is progressing towards engineered materials with tailored properties.