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Related Experiment Video

Updated: Mar 3, 2026

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
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A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

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Feasibility of Endoscopic Closure Method Using Low Cost Clips With Thread for Post Gastric Endoscopic Submucosal

Ryosuke Ikeda1, Hiroaki Kaneko1, Hiroki Sato1

  • 1Department of Gastroenterology Yokohama City University Graduate School of Medicine Yokohama Japan.

JGH Open : an Open Access Journal of Gastroenterology and Hepatology
|March 2, 2026
PubMed
Summary

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This summary is machine-generated.

A new low-cost endoscopic closure (LoCC) method effectively closes gastric endoscopic submucosal dissection (ESD) defects, preventing delayed bleeding. This cost-effective technique offers high success rates without expensive devices.

Area of Science:

  • Gastroenterology
  • Endoscopic Surgery
  • Medical Device Innovation

Background:

  • Endoscopic closure of gastric endoscopic submucosal dissection (ESD) defects is crucial for preventing delayed bleeding.
  • Existing closure methods often incur significant costs, posing a barrier to widespread adoption.
  • There is a need for cost-effective endoscopic closure techniques.

Purpose of the Study:

  • To develop and evaluate a novel low-cost endoscopic closure (LoCC) method for post-ESD gastric ulcers.
  • To assess the feasibility, cost-effectiveness, and efficacy of the LoCC method in a pilot study.

Main Methods:

  • Retrospective analysis of 20 gastric lesions in 18 patients undergoing ESD.
  • Application of the LoCC method using conventional clips and threads for mucosal defect approximation.
Keywords:
clip‐with‐thread methodcost‐effectivenessdelayed bleedingendoscopic submucosal dissectionlow‐cost endoscopic closure

Related Experiment Videos

Last Updated: Mar 3, 2026

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
20:33

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

Published on: July 4, 2019

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  • Evaluation of primary outcome (complete closure rate) and secondary outcomes (closure time, cost, sustained closure, delayed bleeding).

    • Main Results:

    • Complete closure was achieved in 90% of lesions, with 85% showing sustained closure on postoperative day 1.
    • Median closure time was 17.5 minutes, using a median of 20 clips at a cost of $131.8.
    • No instances of delayed bleeding were reported.

    Conclusions:

    • The LoCC method demonstrates favorable technical feasibility and cost-efficiency for closing post-ESD ulcers.
    • The technique achieves high closure and sustained closure rates without requiring expensive specialized devices.
    • LoCC presents a practical and feasible option for routine clinical application in endoscopic submucosal dissection closure.