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Photoluminescence: Applications

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Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...

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A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

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A novel inherent fluorescence biodegradable polyurethane.

Juan Liu^1,2, Shun Li¹, Zhengwei Li¹

¹Research Center for Human Tissue and Organ Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China.

Regenerative Biomaterials

|March 2, 2026

Summary

This summary is machine-generated.

Researchers developed novel fluorescent biodegradable polyurethanes (IFPUs) to precisely control and visualize degradation for tissue regeneration. These materials enable real-time tracking of biodegradability, optimizing tissue repair strategies.

Keywords:

3D printed scaffold biodegradable polyurethane degradation behavior inherent fluorescence regenerative biomaterials

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A Polyaniline-based Sensor of Nucleic Acids

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Published on: November 1, 2016

Area of Science:

Biomaterials Science
Polymer Chemistry
Regenerative Medicine

Background:

Biodegradable biomaterials are crucial for *in situ* tissue regeneration.
Controlling and tracking biomaterial degradation remains a significant challenge.
Matching degradation rates with tissue formation is essential for successful repair.

Purpose of the Study:

To develop novel inherently fluorescent biodegradable polyurethanes (IFPUs).
To enable adjustable and trackable degradation behaviors for tissue engineering.
To elucidate the degradation mechanism of biodegradable polyurethanes.

Main Methods:

Synthesis of IFPUs incorporating fluorescent small molecules (thiazolpyridinic acid).
Characterization of fluorescence, degradation (*in vitro* and *in vivo*), and mechanical properties.
3D printing of porous IFPU scaffolds for tissue engineering applications.

Main Results:

IFPUs exhibit strong fluorescence for real-time degradation visualization.
Degradation rates are adjustable and linked to hard segment hydrophilicity.
3D-printed IFPU scaffolds show high porosity, excellent mechanical strength, and promote cell activity.
Demonstrated excellent *in vivo* biocompatibility.

Conclusions:

IFPUs offer a promising platform for tunable and trackable biodegradable materials in tissue regeneration.
Fluorescent visualization provides a powerful tool to study degradation mechanisms.
These materials hold potential for advanced 3D-printed scaffolds in regenerative medicine.