Association of Sleeve Gastrectomy With the Management of Ovarian Hyperstimulation Syndrome: A Retrospective Study

The rise in global obesity is a major concern with particular implications for female reproductive health. Obesity is considered a risk factor for menstrual disturbances, female infertility, and reduced success rate of assisted reproductive technologies (ARTs). Weight reduction represents a promising therapeutic approach for addressing infertility in female patients who are obese. Nowadays, bariatric surgery is regarded as the most efficacious long-term intervention for morbid obesity, leading to enhanced reproductive health. The impact of bariatric surgery in terms of association and management has also been sparsely studied, and evidence regarding OHSS management after bariatric surgery is limited, highlighting a literature gap.  Objective: Primarily, this study aimed to investigate the association of sleeve gastrectomy with patients who developed ovarian hyperstimulation syndrome (OHSS) in terms of length of hospital stay.  Results: Interestingly, sleeve gastrectomy patients had longer hospital stays, averaging 5.3 ± 0.5 days, as compared to 3.3 ± 2.1 days among non-sleeve gastrectomy patients (p = 0.026).

The association of sleeve gastrectomy with the management of OHSS manifested as a longer hospital stay. We hypothesize that the reduced oral fluid tolerance after the sleeve gastrectomy may contribute to the increased length of hospital stay.