Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Teeth

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...

Cognitive Development During Adulthood

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.

Language and Cognition

Language and Cognition

Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.

Role of Neurotransmitters in Memory

Role of Neurotransmitters in Memory

Neurotransmitters are integral to the brain's communication system, enabling neurons to transmit signals across synapses. This chemical exchange underpins various cognitive functions, including memory processes. The role of neurotransmitters in memory is multifaceted, influencing the encoding, consolidation, and retrieval of memories through their action on different neural circuits.
Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is...

Assessment of the Mouth

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Differential Associations of Oral Health with Early- and Late-Onset Dementia: A Prospective Analysis of the UK Biobank.

The journals of gerontology. Series A, Biological sciences and medical sciences·2026

Same author

National Acceptance and Determinants of Immersive Extended Reality in Health Care in China: Cross-Sectional Study.

Journal of medical Internet research·2026

Same author

Divergent effects of oral health and genetic risk: competing risks of dementia and mortality.

Innovation in aging·2026

Same author

The landscape of knowledge graph and large language model-augmented knowledge graph applications in dementia caregiving support: a scoping review.

The Gerontologist·2026

Same author

Understanding Oral Health Management for People Living With Dementia: A Qualitative Meta-Synthesis.

Gerodontology·2026

Same author

Dementia diagnostic deserts: workforce and geographic inequities in the diagnostic pathway for cognitive impairment.

Health affairs scholar·2026

Search research articles

Related Experiment Video

Updated: Mar 4, 2026

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation

Published on: November 26, 2019

Moderating Effects of Oral Bacteria and Tooth Loss on Cognitive Performance.

H Luo¹, A R Kamer², Z Xu³

¹Brody School of Medicine, East Carolina University, Greenville, NC, USA.

JDR Clinical and Translational Research

|March 2, 2026

Summary

Tooth loss impacts cognitive function, particularly verbal fluency, depending on oral microbiome health. Maintaining oral health is crucial for older adults to support brain health.

Keywords:

cognition dysbiotic index missing teeth modifying effects older adults oral microbiome

More Related Videos

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

Oral Health Assessment by Lay Personnel for Older Adults

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Related Experiment Videos

Last Updated: Mar 4, 2026

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation

Assessing Pupil-linked Changes in Locus Coeruleus-mediated Arousal Elicited by Trigeminal Stimulation

Published on: November 26, 2019

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

Oral Health Assessment by Lay Personnel for Older Adults

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Area of Science:

Neuroscience
Microbiology
Gerontology

Background:

The oral microbiome may impact brain health and cognitive decline.
Limited research exists on how the oral microbiome modifies the tooth loss-cognition relationship.

Purpose of the Study:

To investigate the interaction between tooth loss and oral dysbiosis on cognitive performance in older adults.

Main Methods:

Utilized data from the 2011-2012 National Health and Nutrition Examination Survey (n=677, ages 60-69).
Assessed cognitive performance using standardized tests.
Defined significant tooth loss (≥10 teeth) and high oral dysbiosis (upper tertile of specific bacterial ratios).

Main Results:

A significant interaction was found between tooth loss and oral dysbiosis on the Animal Fluency Test (AFT).
Participants with higher oral dysbiosis and fewer missing teeth exhibited lower scores on the AFT.

Conclusions:

The impact of tooth loss on verbal fluency is contingent on oral bacterial balance.
High oral dysbiosis may negatively affect verbal fluency when tooth loss is minimal.
Promoting periodontal health to reduce oral dysbiosis is recommended for older adults.