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E2F1-mediated 53BP2 lactylation stabilizes p53 to induce cochlear hair cell apoptosis in mouse age-related hearing

Xiaoqin Luo1,2, Jun Liu1, Chanyuan Zhang3

  • 1Department of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Southwest Medical University, Sichuan, 646000, China.

Clinical Epigenetics
|March 2, 2026
PubMed

Keywords:
53BP2 lactylationAge-related hearing lossCochlear hair cell apoptosisE2F1p53

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