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Updated: May 11, 2026

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
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Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants

Published on: February 21, 2015

Single Nucleotide Polymorphism Microarray Analysis Unveils Copy-Number Abnormalities and Genetic Heterogeneity in

Nor Soleha Mohd Dali1, Nursaedah Abdullah Aziz1, Muhamad Farid Zulkifle1

  • 1Cancer Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health, Selangor, Malaysia.

Molecular Genetics & Genomic Medicine
|March 3, 2026
PubMed
Summary

This study analyzed the genomic landscape of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) in Malaysian patients. SNP 6.0 microarray and MLPA revealed copy-number abnormalities, aiding in understanding BCP-ALL genetics.

Keywords:
B‐cell precursor acute lymphoblastic leukemiaMLPASNP 6.0 microarraycopy‐number abnormalitiespediatric

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Comparing Copy Number Variations and SNPs02:26

Comparing Copy Number Variations and SNPs

Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...