Intrinsic PPG-ECG Coupling for Accurate and Low-Power Blood Pressure Monitoring
Sitong Chen1, Hua Luo2, Zhentao Yao2
1Department of Pediatric Pulmonology and Immunology, West China Second University Hospital, Sichuan University, Chengdu, China.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|March 3, 2026
Summary
This study introduces a novel method for continuous blood pressure monitoring by fusing photoplethysmography-electrocardiogram (PPG-ECG) signals. This approach enhances accuracy and reduces power consumption for wearable cardiovascular health devices.
Area of Science:
- Biomedical Engineering
- Cardiovascular Technology
- Wearable Health Devices
Background:
- Continuous blood pressure (BP) monitoring is crucial for cardiovascular disease management.
- Traditional BP monitoring using pulse transit time (PTT) often involves multiple signals, leading to synchronization errors and increased power consumption.
- Existing multi-signal BP monitoring systems face challenges in accuracy, efficiency, and system complexity.
Purpose of the Study:
- To develop an intrinsic signal synchronization strategy for accurate and efficient BP estimation.
- To overcome the limitations of conventional multi-signal BP monitoring methods.
- To create a simplified, low-power wearable sensor patch for continuous BP monitoring.
Main Methods:
- Proposed an intrinsic signal synchronization strategy by coupling photoplethysmography (PPG) and electrocardiogram (ECG) signals into a unified waveform.
- Developed a compact, lightweight chest wearable sensor patch based on this principle.
- Evaluated BP measurement accuracy under static and dynamic conditions.
Main Results:
- Achieved intrinsic synchronization, reducing pulse transit time (PTT) error to less than 15 ms with over 98% detection rate.
- Demonstrated a 43.75% decrease in system power consumption due to reduced data load.
- Reported high BP measurement accuracy (ME ≤ 5 mmHg, STD ≤ 8 mmHg) in diverse scenarios.
Conclusions:
- The proposed PPG-ECG signal coupling strategy simplifies BP monitoring device design and manufacturing.
- This intrinsic synchronization method significantly enhances the accuracy, energy efficiency, and operational lifetime of wearable BP monitors.
- The developed sensor patch offers a promising solution for long-term, continuous cardiovascular health assessment.
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