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Updated: May 9, 2026

Small Bowel Transplantation In Mice
Published on: August 20, 2007
Endoscopic small bowel therapies for type 2 diabetes
Roma Patel1, Zehra Naseem2, Prisha Gattu3
1Gastroenterology, Hepatology and Nutrition Department, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Abstract:
Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux-en-Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the pathophysiology of type 2 diabetes. This has led to the emergence of small bowel endoscopic therapies for type 2 diabetes. These therapies include procedures such as duodenal ablation, luminal liners, endoscopic bypasses, and endoscopic injections.
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