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Related Concept Videos

Longitudinal Research02:20

Longitudinal Research

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Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Musculoskeletal Pain During Late Adolescence: The Generation R Study.

Rosemarijn van Paassen1, Max A van Kessel1, Sita M A Bierma-Zeinstra1

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This summary is machine-generated.

Musculoskeletal pain is common in adolescents, affecting 15.5% of 17-year-olds, with many experiencing chronic symptoms. Previous pain and behavioral issues in younger adolescents predict later pain.

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Area of Science:

  • Adolescent health
  • Musculoskeletal pain epidemiology
  • Longitudinal cohort studies

Background:

  • Musculoskeletal (MSK) pain is a significant health concern in adolescents.
  • Limited understanding exists regarding the development and changes in MSK pain during adolescence.

Purpose of the Study:

  • To determine the prevalence and characteristics of MSK pain in 17-year-old adolescents.
  • To investigate associations between MSK pain and demographic factors, prior pain history, lifestyle, and behavior.

Main Methods:

  • Utilized data from a longitudinal birth cohort study.
  • Assessed MSK pain prevalence, location, and characteristics via questionnaires.
  • Analyzed demographic, BMI, pain history, lifestyle, and behavioral data using descriptive statistics and logistic regression.

Main Results:

  • A prevalence of 15.5% for MSK pain was observed in 2537 participants (mean age 18.7 years).
  • Daily pain was reported by 62.3% of those with MSK pain, with a median duration of 21.5 weeks.
  • Lower back (28.0%), knee (26.2%), and upper back (24.2%) were the most common pain locations. Previous MSK pain at age 13 (OR 2.13) and behavioral problems (OR 1.77) were associated with pain at age 18.7.

Conclusions:

  • MSK pain is prevalent and often chronic in late adolescence.
  • The back and knee are the most frequently affected areas.
  • A history of MSK pain and behavioral issues in early adolescence are significant predictors of MSK pain in later adolescence.