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A Video Protocol of Retroviral Infection in Primary Intestinal Organoid Culture
Published on: August 11, 2014
Animal organoids as transformative platforms for viral infections and zoonotic cross-species viral research
Inés García-Rodríguez1, Isabel García-Dorival2, Covadonga Alonso1
1Departamento de Biotecnología, CSIC-INIA, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Madrid, Spain.
Abstract:
Organoids have revolutionized human biomedical research since their development in 2010. However, as nearly 75% of human infectious diseases originate in animals, animal-derived organoids are essential to complement human models, yet their development in veterinary contexts remains scarce. Organoids replicate native tissue architecture, enabling species-specific and comparative studies of viral infection and host response. Thus, animal organoids represent a powerful field in organoid technology, advancing cross-species virology research and strengthening strategies for zoonotic disease preparedness.
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