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Esophageal Perforation-I: Introduction

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Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
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Related Experiment Video

Updated: Mar 4, 2026

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

Sarcopenia in gallbladder perforation: a radiological comparison study.

Utku Eren Ozkaya¹, Turay Cesur², Bilal Egemen Cifci³

¹Department of Radiology, Ministry of Health Cigli Education Hospital, İzmir, Turkey. utkuerenozkaya@gmail.com.

Abdominal Radiology (New York)

|March 3, 2026

Summary

This summary is machine-generated.

Sarcopenia, a loss of muscle mass, is linked to subacute gallbladder perforation (GBP) and less frequent surgery. Early CT detection of sarcopenia aids in risk stratification for GBP patients.

Keywords:

Cholecystitis Computed tomography Gallbladder Intra-abdominal fat Sarcopenia

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Non-invasive Skeletal Muscle Quantification in Small Animals Using Micro-computed Tomography

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Area of Science:

Abdominal Surgery
Radiology
Geriatric Medicine

Background:

Gallbladder perforation (GBP) is a severe complication of acute cholecystitis (AC).
The roles of sarcopenia and visceral adiposity in GBP subtypes and management are not well understood.
These body composition factors may influence outcomes in surgical and emergency settings.

Purpose of the Study:

To investigate the association between sarcopenia, visceral adiposity, and GBP type.
To determine the relationship with treatment preferences and overall mortality in GBP patients.
To evaluate the clinical significance of body composition in managing GBP.

Main Methods:

Retrospective analysis of 89 adult GBP patients (2019-2024).
Body composition assessed via CT scans (L3 level): skeletal muscle index (SMI), intramuscular adipose tissue content (IMAC), visceral-to-subcutaneous fat ratio (VSR).
Logistic regression and Kaplan-Meier analyses were employed to correlate findings with clinical outcomes.

Main Results:

Low SMI was significantly associated with type 2 GBP (subacute perforation).
Patients with low SMI showed a preference for percutaneous cholecystostomy catheter drainage (PCCD) over urgent surgery.
Higher mortality was observed in the low SMI group in univariate analysis (p=0.015).

Conclusions:

Sarcopenia is linked to subacute (type 2) gallbladder perforation.
Sarcopenia may influence treatment decisions, favoring less invasive approaches like PCCD.
CT-based detection of sarcopenia can aid in risk stratification and clinical management of GBP.