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Dissolving microneedles for cellulitis: a systematic review.

Arya Tripathi¹, Molakpogu Ravindra Babu¹, Sarad Pawar Naik Bukke²

¹Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India.

Journal of Biomaterials Science. Polymer Edition

|March 3, 2026

Summary

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This summary is machine-generated.

Antibacterial dissolving microneedles (DMNs) show promise for treating cellulitis, a common skin infection. This review found DMNs offer better results than traditional methods for skin infections.

Area of Science:

Biomedical Engineering
Dermatology
Infectious Diseases

Background:

Cellulitis is a prevalent bacterial skin infection.
Conventional treatments have limitations.
Dissolving microneedles (DMNs) offer enhanced drug delivery properties.

Purpose of the Study:

To systematically review the effectiveness of antibacterial DMNs for cellulitis treatment.
To compare DMN efficacy against conventional therapies.

Main Methods:

Systematic review conducted following PRISMA guidelines.
Searched Google Scholar, PubMed, and Scopus databases.
Included 18 studies after applying inclusion/exclusion criteria.

Main Results:

Keywords:

Dissolving microneedles antibacterial therapy biofilm cellulitis minimally invasive treatment skin infection transdermal delivery

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DMNs demonstrated superior physicochemical properties for skin penetration and bioavailability.
Antibacterial DMNs showed better therapeutic outcomes compared to conventional treatments.
DMNs represent a promising minimally invasive approach for skin infections.

Conclusions:

DMNs are an effective and promising minimally invasive treatment for cellulitis.
Further research into DMNs for skin infections is warranted.