Management and work-up procedures of patients with head and neck malignancies treated by radiation: 2025 update

Radiotherapy alone or in association with systemic treatment plays a major role in the treatment of head and neck tumours, either as a primary treatment or as a postoperative modality. The management of these tumours is multidisciplinary, requiring particular care at every treatment step. We present the 2025 update of the recommendations of the Société française de radiothérapie oncologique (the French society for radiation oncology) on the radiotherapy of head and neck tumours from the imaging work-up needed for optimal selection of treatment volume, to optimization of the dose distribution and delivery.