Diagnosis and management of pediatric and adolescent hereditary angioedema: A clinical yardstick

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Andrew MacGinnitie1, Timothy J Craig2, Jonathan A Bernstein3

  • 1Division of Allergy, Asthma, and Immunology, Children's Wisconsin and Medical College of Wisconsin, Milwaukee, Wisconsin.

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|March 3, 2026
PubMed

There have been significant breakthroughs in understanding the pathophysiology of hereditary angioedema in the past several years. Owing to this, patients now have several therapeutic options for management of both acute attacks and prophylactic therapy. Navigating these options can be confusing to patients and clinicians alike. This is even more evident in the pediatric and adolescent populations secondary to differing lifestyles in these age groups, needing to understand the goals of various family members, and differing ages of approvals for medications. This Yardstick provides evidence-based, expert opinion on how to diagnose and manage pediatric and adolescent hereditary angioedema.

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