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Updated: Jul 1, 2026
11:21
Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Integrated LC-OCT/Raman Microspectroscopy: A Novel Diagnostic Approach in Ophthalmology Demonstrated in a Case Study
Ayadh Meriem1, Dorado Cortez Christian1, Ogien Jonas2
1Dermatology Department, University Hospital of Saint-Etienne, Saint-Etienne, France.
Journal of Biophotonics
|March 3, 2026
Summary
Integrated optical coherence tomography (OCT) and Raman microspectroscopy non-invasively identify conjunctival hydroxyapatite calcifications. This dual approach detects microcrystals missed by conventional histology.
Area of Science:
- Ophthalmology
- Biomedical Optics
- Materials Science
Background:
- Conjunctival calcifications, particularly hydroxyapatite microcrystals, pose diagnostic challenges.
- Conventional histology often fails to detect these microcrystals due to solubility and weak birefringence.
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