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Updated: May 5, 2026
Robot-Assisted Radical Antegrade Modular Pancreatosplenectomy Including Resection and Reconstruction of the Spleno-Mesenteric Junction
Published on: January 3, 2020
Long-term oncologic outcomes of robot-assisted radical cystectomy: Prognostic indicators and complication profiles
Sung Goo Yoon1, Tae Young Park1, Hyun Jung Jin1
1Department of Urology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
Purpose:
Robot-assisted radical cystectomy (RARC) is globally accepted, but single-surgeon, high-volume data linking perioperative factors with long-term oncologic outcomes are limited.
Materials And Methods:
We retrospectively reviewed 304 consecutive RARC cases performed by one surgeon between 2007 and 2024. Total intracorporeal urinary diversion (ICUD) was used in 73.0% of patients and orthotopic neobladder (ONB) reconstruction in 64.5%. Median follow-up was 51.21 months. Primary endpoints were overall survival (OS), cancer-specific survival (CSS), and recurrence-free survival (RFS). Secondary endpoints included complication profiles and pentafecta, defined as margin-negative resection, ≥16 or more lymph nodes, no Clavien-Dindo grade ≥3 or higher complication within 90 days, no recurrence within 12 months, and no ureteroenteric stricture.
Results:
Mean operative time was 447.61 minutes, median lymph-node yield was 31.0 in the extended PLND group and 24.0 in the standard PLND group, and the positive margin rate was 1.0%. ICUD was associated with shorter hospitalization than extracorporeal diversion (13.81 days vs. 17.03 days, p=0.026) and fewer early high-grade complications. Seven-year OS, CSS, and RFS were higher in pentafecta achievers (69.3%, 94.2%, and 82.6%), and 7-year OS was also superior in patients with organ-confined (≤T2) and node-negative disease (69.0% vs. 28.6% and 67.5% vs. 19.4%). Complications occurred in 59.7% overall, with 14.9% major; infections were most common (20.7%).
Conclusions:
In a high-volume single-surgeon series, RARC with ICUD provided durable oncologic control, acceptable morbidity, and high pentafecta achievement. Pathologic T and N stage and pentafecta were significant prognostic indicators that may assist in refining patient selection, guiding postoperative surveillance, and informing survivorship care.
