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Updated: May 5, 2026

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
Published on: January 21, 2018
Cardiovascular complications of cellular immunotherapies and associated risk factors
Eli Grunblatt1, Nausheen Akhter2
1Department of Medicine, Feinberg School of Medicine, Northwestern University, 676 N. St. Clair, Suite 2330, Chicago, IL, 60611, USA.
Abstract:
In recent years, the use of cellular immunotherapies has become widespread for the treatment of patients with refractory malignancies. While this has led to improved overall outcomes, these therapies have been associated with numerous, sometimes severe cardiotoxicities. In this review, we highlight the spectrum of cardiovascular adverse events that can occur following cellular immunotherapies with a particular emphasis on the pre-treatment risk factors that may be associated with these cardiotoxicities.
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