Family history of premature CHD and risk factor control in patients with a recent ACS
Daniel Yu-Hung Jeng1,2, Haeri Min3, Simone Marschner3
1Sydney Medical School, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia. danieljeng57@gmail.com.
Insights
Knowing about a family history of premature heart disease (CHD) did not significantly improve risk factor control in patients after an acute coronary syndrome (ACS). Novel strategies are needed for better secondary prevention in this high-risk group.
Area of Science:
- Cardiology
- Preventive Medicine
- Public Health
Background:
- A family history of premature coronary heart disease (CHD) is a significant risk factor for cardiac events.
- Individuals with a family history may be motivated to adopt healthier behaviors for secondary prevention after experiencing an acute coronary syndrome (ACS).
Purpose of the Study:
- To investigate if a self-reported family history of premature CHD influences risk factor and health behavior control at 12 months post-ACS.
- To assess the association between family history knowledge and outcomes like blood pressure control, LDL cholesterol, BMI, exercise, and smoking status.
Main Methods:
- Analysis of data from the TEXTMEDS study.
- Inclusion of 1423 participants (556 with family history, 867 without).
- Evaluation of risk factor control (blood pressure, LDL cholesterol, BMI) and health behaviors (exercise, smoking) at 12 months post-ACS.
Main Results:
- No statistically significant evidence was found indicating that patients aware of their family history achieved better control of risk factors.
- The presence of a family history of premature CHD did not correlate with improved health behaviors at 12 months post-ACS.
Conclusions:
- Knowledge of a family history of premature CHD alone is insufficient to drive improved secondary prevention outcomes post-ACS.
- There is a critical need for developing and implementing novel strategies to enhance risk factor control and secondary prevention in patients with a family history of CHD.
Abstract:
Individuals with a family history of premature coronary heart disease (CHD) have increased cardiac morbidity and mortality, which may motivate them to modify their health behaviours. This analysis examines whether patients with self-reported family history of premature CHD experiencing an acute coronary syndrome (ACS) were more likely to have their risk factors and health behaviours under control at 12 months post ACS. Data from the TEXTMEDS study were used to estimate the association between self-reported family history of premature CHD and blood pressure control, LDL cholesterol control, BMI, exercise and smoking status at 12 months post ACS. The study cohort consisted of 1423 participants (mean age 58.0 ± 10.67, 79.2% male), with 556 (39.1%) reporting a family history of premature CHD, while 867 (60.9%) reported no family history. No evidence from this analysis suggests that patients with knowledge of their family history were more likely to achieve better risk factor control. Novel strategies for risk factor control in this high-risk population is required to improve secondary prevention.
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