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Synthesis and Characterization of Functionalized Metal-organic Frameworks
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Selective decarboxylative dimerization enabled by a supramolecular template on Ag(111).

Haiwei Wang1, Xianfei Xu2, Zhaokun Wang3

  • 1State Key Laboratory of Green Chemical Synthesis and Conversion, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, CN 310014, China. lijin@zjut.edu.cn.

Physical Chemistry Chemical Physics : PCCP
|March 4, 2026
PubMed
Summary

Supramolecular ribbons of heptaazaphenalene-tribenzoic acid (HTBA) on silver surfaces direct decarboxylative coupling reactions. This molecular templating achieves high selectivity (>90%) for a specific dimer, overcoming challenges in surface-confined organic synthesis.

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Area of Science:

  • Surface science
  • Organic chemistry
  • Supramolecular chemistry

Background:

  • On-surface synthesis faces challenges in achieving high selectivity.
  • Controlling reaction pathways in multi-functional molecules on surfaces is complex.

Purpose of the Study:

  • To investigate the decarboxylative coupling reactions of heptaazaphenalene-tribenzoic acid (HTBA) on the Ag(111) surface.
  • To understand how supramolecular assembly influences reaction selectivity.

Main Methods:

  • Scanning Tunneling Microscopy (STM) for temperature-dependent measurements.
  • In situ heating to observe reaction dynamics.
  • Control experiments under pseudo-high dilution conditions.

Main Results:

  • A thermally persistent supramolecular ribbon assembly of HTBA was formed on Ag(111).
  • Sequential annealing predominantly (>90%) yielded a single dumbbell-shaped dimer from HTBA.
  • Anisotropic steric confinement and inter-ribbon displacement within the assembly directed selectivity.
  • Dimer formation was suppressed under pseudo-high dilution, confirming templating effects.

Conclusions:

  • Supramolecular organization can effectively regulate reaction selectivity in multi-functional molecules on surfaces.
  • Molecular templating within stable assemblies provides a strategy for high-selectivity on-surface synthesis.
  • The study offers mechanistic insights into surface-confined reaction control.