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Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Linking patient records at scale with a hybrid approach combining contrastive learning and deterministic rules
Cheng Cao1, Jay Pillai1, Sara Daraei1
1Truveta Inc., 1745 114th Ave SE, Bellevue, WA 98004, United States.
None:
Linking patient records across disparate healthcare systems is essential to create comprehensive views of patient health, yet this task is complicated by inconsistent identifiers and data quality issues. Although traditional deterministic and probabilistic record linkage (RL) methods have long been used for this purpose, deterministic approaches are brittle in the presence of noisy personally identifiable information (PII), while probabilistic approaches are often difficult to scale. As a result, large-scale linkage commonly relies on restrictive matching strategies that limit recall. This work presents a hybrid RL approach that integrates a deep embedding model with deterministic rules, leveraging both the flexibility and noise robustness of soft embeddings and the reliability and predictable baseline performance of deterministic rules. Using a large-scale real-world dataset, a BERT-based embedding model is fine-tuned in a Siamese network with contrastive loss to encode PII fields as numeric vectors. De-duplicated identifiers (Fuzzy IDs) are then obtained through a blocking-and-clustering step using the embedding vectors. The approach is evaluated using multiple signals (social security number, phone, and email) and is shown to outperform baseline methods. A postprocessing step based on deterministic rules allows embedding-based linkage to be overridden in a subset of cases where high-confidence rules apply, such as when a high-quality identifier is available. The system is deployed on a commercial database consisting of more than 200 million PII records, demonstrating scalability in a real-world healthcare setting.
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