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Related Concept Videos

Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Introduction to Fibroblasts01:09

Introduction to Fibroblasts

Rudolph Virchow discovered spindle-shaped cells called fibroblasts in 1858. Inactive fibroblasts, called fibrocytes, become activated by various stimuli, such as growth factors and inflammatory cytokines. Activated fibroblasts play a crucial role in wound healing, inflammation, formation of new blood vessels, and cancer progression. Uncontrolled activation of fibroblasts results in fibrosis, the excess deposition of fibrous tissue, which can lead to scarring and affect normal organs. This...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...

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Related Experiment Video

Updated: Jul 16, 2026

Murine Dermal Fibroblast Isolation by FACS
06:04

Murine Dermal Fibroblast Isolation by FACS

Published on: January 7, 2016

Case Report: Rare vulvar myofibroblastoma.

Jiaxin Miao1, Shaoqin Sheng2, Xiangqian Xu3

  • 1The Fourth Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China.

Frontiers in Oncology
|March 4, 2026
PubMed
Summary

Vulvar myofibroblastoma is a rare tumor with uncertain malignant potential. Complete surgical resection and long-term follow-up are crucial for managing this vulvar mass.

Area of Science:

  • Gynecologic Oncology
  • Surgical Pathology
  • Rare Tumors

Background:

  • Vulvar myofibroblastoma is a rare mesenchymal tumor of myofibroblasts.
  • Its pathogenesis and malignant potential remain unclear, often considered low-grade or uncertain.
Keywords:
case reportclinicopathological featuresdiagnosis and treatment strategiessurgical managementvulvar myofibroblastoma

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