Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

671
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
671
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

495
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
495
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

558
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
558

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Outcomes of Complete Revascularization in Acute Myocardial Infarction Patients With High Bleeding Risk and Multivessel Disease.

Journal of the American Heart Association·2026
Same author

Diabetes and Risk of Radial Artery Occlusion After Distal Radial Access: Insights From the KODRA Registry.

Heart, lung & circulation·2026
Same author

Video frame interpolation for coronary angiography using latent flow matching.

NPJ digital medicine·2026
Same author

Comparative effectiveness of Orsiro, Xience, Synergy, and Resolute stent in patients with acute myocardial infarction undergoing percutaneous coronary intervention: a nationwide registry study.

Coronary artery disease·2026
Same author

Comparison of Clinical Outcomes Between Incomplete and Complete Revascularization in NSTEMI Patients With Multivessel Disease.

JACC. Asia·2026
Same author

Discontinuation of Beta-Blocker Therapy after Myocardial Infarction.

The New England journal of medicine·2026
Same journal

Cardiovascular Health Change Patterns After Multifaceted Antihypertensive Intervention and Cardiovascular Outcomes: A Post Hoc Analysis of CRHCP Trial.

Journal of the American College of Cardiology·2026
Same journal

Natural History of Asymptomatic Phenotypically Mild HCM: Insights From the SHaRe Registry.

Journal of the American College of Cardiology·2026
Same journal

Preparing for Tomorrow, Today: Identifying Predictors of Future Cardiac Complications in Patients With Mild Hypertrophic Cardiomyopathy.

Journal of the American College of Cardiology·2026
Same journal

Environment and the Heart: Measuring the Health Impact of Environmental Risks and Making It Matter.

Journal of the American College of Cardiology·2026
Same journal

Soft Timing, Hard Thresholds, and Myocardial Injury Reclassification With hs-cTnT-gen6.

Journal of the American College of Cardiology·2026
Same journal

High-Sensitivity Cardiac Troponin T-gen 6 Assay and Analytical Imprecision Still a Concern for the Derived Deltas.

Journal of the American College of Cardiology·2026
See all related articles

Related Experiment Video

Updated: May 3, 2026

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
12:00

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

Published on: November 24, 2014

15.9K

Intravascular Imaging- vs Angiography-Guided Complex PCI: 5-Year Outcomes From a Randomized Trial.

Joo Myung Lee1, Onyou Kim2, Young Bin Song1

  • 1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Journal of the American College of Cardiology
|March 4, 2026
PubMed
Summary
This summary is machine-generated.

Intravascular imaging guidance significantly lowers the risk of major adverse cardiac events in patients with complex coronary artery lesions undergoing percutaneous coronary intervention (PCI). This approach proved superior to traditional angiography guidance in a long-term clinical trial.

Keywords:
coronary artery diseaseintravascular imagingintravascular ultrasoundoptical coherence tomographypercutaneous coronary interventionrandomized controlled trial

More Related Videos

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.6K
Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound
13:48

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Published on: April 21, 2023

2.1K

Related Experiment Videos

Last Updated: May 3, 2026

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
12:00

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

Published on: November 24, 2014

15.9K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.6K
Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound
13:48

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Published on: April 21, 2023

2.1K

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Imaging

Background:

  • Long-term outcome data for intravascular imaging-guided percutaneous coronary intervention (PCI) in complex coronary artery lesions are limited.
  • Comparison with traditional angiography-guided PCI is crucial for understanding treatment benefits.

Purpose of the Study:

  • To evaluate and compare the long-term clinical outcomes of intravascular imaging-guided PCI versus angiography-guided PCI in patients with complex coronary artery lesions.
  • To determine if imaging guidance offers superior outcomes in this patient population.

Main Methods:

  • A prospective, multicenter, open-label superiority trial (RENOVATE-COMPLEX-PCI) was conducted in South Korea.
  • 1,639 patients with complex coronary artery lesions were randomized 2:1 to either intravascular imaging-guided PCI or angiography-guided PCI.
  • The primary endpoint was a composite of cardiac death, target vessel-related myocardial infarction, or clinically driven target vessel revascularization.

Main Results:

  • At a median follow-up of 5.3 years, the primary endpoint occurred in 10.5% of the imaging-guided group versus 14.9% in the angiography-guided group (HR: 0.68; P=0.009).
  • Specific event rates showed reductions in cardiac death/myocardial infarction and revascularization with imaging guidance.
  • No significant differences in procedure-related safety events were observed between the two groups.

Conclusions:

  • Intravascular imaging guidance significantly reduces the risk of major adverse cardiac events in patients with complex coronary artery lesions undergoing PCI.
  • The findings support the use of intravascular imaging guidance for improved long-term outcomes in complex PCI.
  • The study provides robust evidence for the superiority of imaging guidance over angiography guidance in this setting.