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Over-the-Counter Product Use Among Individuals with Vitiligo: A Cross-Sectional International Survey
N O Enwereji1, O C Opaigbeogu2, A Geisler3
1Department of Dermatology, Wayne State University School of Medicine, Detroit, MI, USA.
Clinical Drug Investigation
|March 4, 2026
Summary
Many vitiligo patients use over-the-counter (OTC) products due to dissatisfaction with conventional treatments. Camouflage emerged as the most beneficial OTC, suggesting its inclusion in vitiligo management plans.
Area of Science:
- Dermatology
- Patient-reported outcomes
- Complementary and alternative medicine
Background:
- Vitiligo management presents challenges, impacting patient quality of life.
- Many individuals with vitiligo utilize complementary and alternative medicine (CAM) alongside or instead of conventional therapies.
- Over-the-counter (OTC) products, including CAMs and camouflage, are frequently explored by patients.
Purpose of the Study:
- To investigate the motivations and demographics of vitiligo patients using OTCs.
- To identify the most utilized OTC products within the vitiligo population.
- To assess the perceived efficacy and side effects of commonly used OTCs for vitiligo.
Main Methods:
- An international, observational, cross-sectional study was conducted.
- An anonymous digital questionnaire was distributed to adults diagnosed with vitiligo.
- Participants reported on their use of predefined OTC products and open-ended options.
Main Results:
- 41.1% of vitiligo patients used OTCs, driven by dissatisfaction with conventional treatments, side effect concerns, and cost.
- The most common OTCs included camouflage, Vitamin B12, Vitamin D, zinc, ginkgo biloba, and Vitamin C.
- Camouflage was identified as the most helpful OTC, with mild side effects reported by 6.3% of users.
Conclusions:
- Healthcare providers should be aware of prevalent OTC use among vitiligo patients.
- Patient concerns regarding conventional treatments warrant consideration in management and drug development.
- Incorporating camouflage into treatment plans may enhance patient satisfaction and management strategies.
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